A street with a 'Little Italy' sign, parked cars, and buildings with Italian flags.

Little Italy Vacations from $279

Book a Hotel + Flight or Car together to unlock savings

Your Little Italy Vacation

Get lost in the magic of this trendy neighborhood with a Little Italy vacation package. From its shopping and cafes to its dining, there's lots here for everyone. Not sure what to do during your trip to Little Italy? Nearby attractions like San Diego Zoo, Balboa Park and Petco Park are good places to start. Expedia will help put your plans into action. Book your perfect Little Italy vacation today.

The Latest Little Italy Vacation Packages

Price found within the past 48 hours. Click for updated prices.
  • A multi-story hotel with a brick facade, multiple windows, and a fire escape.
    Jan 22 - Jan 24

    The Sofia Hotel + Flight

    Downtown San Diego
    2 nights
    3.5 star property
    8.8/10 - Excellent (2,766 reviews)
    "Really enjoyed my stay at The Sofia. My room had a nepresso coffee machine which was great. Very clean and quiet, close to the convention center and easily walkable to restaurants, shopping and sight seeing."
    Reviewed November 6, 2026
    Roundtrip • Denver (DEN) - San Diego (SAN)
    DEN - SAN • Nonstop SAN - DEN • Nonstop
    Save 100% on your flight
    $435
    $279
    per traveler
    found 1 day ago
    The Sofia Hotel
  • A balcony with wicker furniture, a stone building, and a view of the ocean and golf course.
    Jan 15 - Jan 18

    Pantai Inn + Flight

    Village of La Jolla
    3 nights
    3.5 star property
    9.4/10 - Exceptional (1,001 reviews)
    Roundtrip • Denver (DEN) - San Diego (SAN)
    DEN - SAN • Nonstop SAN - DEN • Nonstop
    $1,569
    $950
    per traveler
    found 10 hours ago
    Pantai Inn
  • A spacious lobby with modern furniture, large windows, and a high ceiling with hanging lights.
    Jan 11 - Jan 15

    Legacy Resort Hotel & Spa + Flight

    Mission Valley
    4 nights
    4.0 star property
    9.2/10 - Wonderful (3,094 reviews)
    Roundtrip • Denver (DEN) - San Diego (SAN)
    DEN - SAN • Nonstop SAN - DEN • Nonstop
    $560
    $351
    per traveler
    found 17 hours ago
    Legacy Resort Hotel & Spa
  • A hotel room with two beds, a large mirror, a wooden headboard, and a carpeted floor.
    Jan 29 - Feb 1

    Hotel Z + Flight

    Downtown San Diego
    3 nights
    3.0 star property
    9.2/10 - Wonderful (1,224 reviews)
    "Nice place"
    Reviewed November 3, 2026
    Roundtrip • Denver (DEN) - San Diego (SAN)
    DEN - SAN • Nonstop SAN - DEN • Nonstop
    Save 100% on your flight
    $557
    $351
    per traveler
    found 10 hours ago
    Hotel Z
  • A resort with a large swimming pool, multiple buildings, and surrounding greenery.
    Jan 12 - Jan 16

    Fairmont Grand Del Mar + Flight

    Carmel Valley
    4 nights
    5.0 star property
    9.4/10 - Exceptional (1,001 reviews)
    "Excellent property and stay"
    Reviewed November 6, 2026
    Roundtrip • Seattle (SEA) - San Diego (SAN)
    SEA - SAN • Nonstop SAN - SEA • Nonstop
    Save 100% on your flight
    $1,928
    $1,220
    per traveler
    found 7 hours ago
    Fairmont Grand Del Mar

Where to stay in Little Italy

Find the best Little Italy areas and neighborhoods for the activities you enjoy most. Learn more about Little Italy
Learn more about Little Italy
A large stadium with the sign "Cobo Park" and palm trees around it.

Downtown San Diego

Cultural and financial hub, Downtown San Diego boasts the Symphony, Opera, theaters, museums, and historic sites like Gaslamp Quarter. Enjoy diverse shops, dining, nightlife, and convenient public transport options.

A pier extending into the ocean with buildings at the end, under a partly cloudy sky.

Pacific Beach

Boasting a lively nightlife scene, Pacific Beach offers miles of sandy shores, a bustling 3.2-mile boardwalk, and attractions like Crystal Pier and Kate Sessions Park. Enjoy local shops, bars, and eateries along the vibrant walkway.

A theater marquee with ornate designs and the name "Gaslamp Quarter".

Gaslamp Quarter

Downtown San Diego's historic district boasts Victorian-era buildings, now housing vibrant restaurants, shops, and entertainment venues. Stroll from Broadway to Harbor Drive, and 4th to 6th Avenue, admiring the newly installed gaslamps at Market Street.

A coastal cityscape with a long sandy beach, a pier, and dense urban buildings.

Mission Beach

Spanning nearly two miles of oceanfront, this sandbar community offers sunbathing, surfing, and beach volleyball, with nearby attractions like Belmont Park's Giant Dipper Roller Coaster and SeaWorld in Mission Bay Park.

An aerial view of a coastal city with a marina, a large body of water, and a peninsula with buildings.

Mission Bay

If you're spending some time in Mission Bay, Mission Bay and Ski Beach are top sights worth seeing.

Discover the most popular places to visit in Little Italy

A cityscape with modern high-rise buildings, a water fountain area, and people enjoying the park.

Waterfront Park

9.2/10 (64 reviews)
A fountain with an enormous basin in which kids can splash around creates a fun and welcoming attraction for the whole family.
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What to do near Little Italy

LEGOLAND® California Resort

LEGOLAND® California Tickets

$91
per adult
84% of travelers recommend
LEGOLAND® California Tickets
See all activities near Little Italy

Little Italy Hotel Deals

A modern lobby with a green sofa, a wooden accent wall, and a large plant.

Little Italy Inn - Limited Service Apart Hotel

Little Italy Inn - Limited Service Apart Hotel
2.5 star property
Little Italy
8.4 out of 10, Very good, (408 reviews)
$108 nightly
The price is $124
Nov 9 - Nov 10
Total with taxes and fees
Little Italy Inn - Limited Service Apart Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
See all properties in Little Italy
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.